CARE Perspectives ASH 2015

Members of the CARE Hematology Faculty recently attended the American Society of Hematology (ASH) 2015 conference held in Orlando, Florida from December 5-8. The 10th annual CARE at ASH meeting was held on Friday, December 4th and was attended by upwards of 85 trainees and specialists in the community of practice. Leading Canadian specialists spoke on a number of exciting topics in the field of hematology. 

The CARE Perspectives ASH Report provides:

  • A summary of the most compelling stories and news presented at this annual event 
  • Expert perspectives from the CARE Hematology Faculty
  • Supportive CARE considerations 
 
 


CARE Perspectives CHC 2015

CARE Education is pleased to have successfully completed the 5th annual Canadian Hematology Conference (CHC 2015), held on October 2-3 in Toronto, Ontario. 

This two day conference brings together a pan-Canadian and international Faculty of KOLs to showcase news and developments in hematological malignancies. Presentations featured cutting edge content with discussion on relevant cases and treatment strategies.

CHC 2015 is the largest multidisciplinary hematology focused meeting in Canada, attended by over 150 Canadian hematology professionals. Attendees included academic and community specialists, residents, nurses and pharmacists with an interest in hematology.

The CARE Perspectives Conference Report from CHC 2015 provides a summary of content presented by leading Canadian specialists as well as several International hematologists at the event, chaired by Drs. John Kuruvilla & Peter Anglin. 

Below is a link to the full report:

click here for the full report

click here for the full report

 


CARE Perspectives IWCLL 2015

Members of the CARE Hematology Faculty recently attended the IWCLL 2015 conference held in Sydney, Australia (September 7-9).

The CARE Perspectives Conference Report from IWCLL 2015 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspective from the CARE Hematology Faculty. 

CLICK HERE TO VIEW THE FULL REPORT

CLICK HERE TO VIEW THE FULL REPORT

 

CARE Perspectives IMW 2015

Members of the CARE Hematology Faculty recently attended the 2015 International Myeloma Workshop (IMW) September 23-26 in Rome, Italy.

The CARE Perspectives Conference Report from IMW provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Hematology Faculty. 

Below is a link to the full report:

CLICK HERE TO VIEW THE FULL REPORT

CLICK HERE TO VIEW THE FULL REPORT

 

CARE Perspectives EHA 2015

Click here to view the full CARE Perspectives EHA 2015 Conference Report. 

Click here to view the full CARE Perspectives EHA 2015 Conference Report. 

Members of the CARE Hematology Faculty recently attended the European Hematology Association (EHA) 2015 conference held in Vienna, Austria (June 11-14).

The CARE Perspectives Conference Report from EHA provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Hematology Faculty. 

Below is a link to the full report:

Click here for the full report.

Click here for the full report.

 

PMCC Multiple Myeloma Day: Update on Multiple Myeloma

Click here to view the full PMCC Multiple Myeloma Day: Update on Multiple Myeloma.

Click here to view the full PMCC Multiple Myeloma Day: Update on Multiple Myeloma.

Princess Margaret Cancer Centre (PMCC) ran its annual PMCC-Multiple Myeloma day meeting on June 19th, 2015. This meeting was attended by leading myeloma specialists, allied health care providers, and pharmacists. Content focused on a number of areas of interest in multiple myeloma, such as relapsed myeloma, post-transplant strategies, and how to personalize myeloma treatment. These are the key topics that are summarized throughout this document.

The content that follows is written in the language in which it was presented. Content is adapted from select presentations and round table discussion from PMCC-MM Day, and is augmented with content and perspectives from the CARE Hematology Faculty. 

Below is a link to the full update as well as a supplementary publication:

Click here for the full update. 

Click here for the full update. 

Click here to read the full CARE Perspectives ICML 2015 Conference Report.

Click here to read the full CARE Perspectives ICML 2015 Conference Report.

 

CARE Perspectives ICML 2015

Click here to read the full CARE Perspectives ICML 2015 Conference Report. 

Click here to read the full CARE Perspectives ICML 2015 Conference Report. 

Members of the CARE Hematology Faculty recently attended the International Conference on Malignant Lymphoma (ICML) held in Lugano, Switzerland (June 17-20). This meeting was attended by 3,000 specialists including hematologists, clinical oncologists, radio- oncologists, paediatricians, pathologists and leading researchers involved in the study and treatment of lymphoid neoplasms.

The CARE Perspectives Conference Report from ICML provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Hematology Faculty. 

Below is a link to the full report as well as a supplementary publication:

Click here for the full report.

Click here for the full report.

Click here to read the full PMCC Multiple Myeloma Day: Update on Multiple Myeloma. 

Click here to read the full PMCC Multiple Myeloma Day: Update on Multiple Myeloma. 

 

CARE Perspectives ASCO Hematology 2015

Click here to view the CARE Perspectives ASCO 2015 hematology Conference Report. 

Click here to view the CARE Perspectives ASCO 2015 hematology Conference Report. 

Members of the CARE (Community. Academic. Research. Education) Oncology and Hematology Faculties recently met at the ASCO 2015 conference held in Chicago from May 29 – June 2. The CARE Resident and Trainee Education meeting was held on May 29th (8:00 am - 1:00 pm). At this meeting CARE Faculty members presented on a number of key topics in oncology, including hematology. The CARE Hematology Faculty then held a separate breakout session after the main meeting that took a deeper look at themes in hematology-oncology. The focus of their discussion was on indolent non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, multiple myeloma, and basic science for antibody drug conjugates. Additionally, due to the exciting news surrounding novel agents in the field of hematology, supportive care considerations for better patient symptom management were addressed at ASCO. This report covers some of the most important story lines in supportive care from ASCO.

The CARE Perspectives Conference Report from ASCO 2015 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Hematology Faculty. 

Below is a link to the full report:

Click here for the full report.

Click here for the full report.

 

Hema-Times: Understanding the Mechanisms of Action of Multiple Myeloma Therapies and their Clinical Implications

Hema-Times: Understanding the Mechanisms of Action of Multiple Myeloma Therapies and their Clinical Implications

Multiple myeloma (MM) is a plasma cell malignancy based in the bone marrow, in which standard treatments have historically included corticosteroids (e.g. dexamethasone and prednisone) and cytotoxic drugs (e.g. melphalan, vincristine, cyclophosphamide, and doxorubicin). However, the treatment paradigm is shifting away from classical chemotherapy to therapies that more directly target the unique plasma cell biology. This may be either through pathways unique to the plasma cell itself or the tumour microenvironment upon which they are dependent. Significant improvements in overall survival and remission duration in multiple myeloma (MM) are largely due to the advent of novel therapeutic agents, including proteasome inhibitors (PIs) and immunomodulatory drugs (IMiDs). Newer agents, including those that affect the epigenome, and antibody-based therapies that directly target the plasma cell are also coming into play. As the therapeutic landscape widens, it will be important to study these agents and their mechanisms of action (MoA).

This paper will focus on the MoA of existing and new agents, in order to promote a better understanding of how they work, and what their implications are in the Canadian clinical setting. 

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CARE Perspectives CCOLD 2015

Members of the CARE Hematology Faculty recently met at the CCOLD 2015 (Canadian Conference on Lymphoproliferative Disorders) conference held in Banff, AB on March 20-22, 2015. A warm thanks to Dr. Wendy Lam and the planning committee for organizing this meeting.

The CARE Perspectives CCOLD 2015 conference report provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspective from the CARE Hematology Faculty. The results of a recent CARE needs assessment focused on subsequent entry biologics are included in this report. 

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Subsequent Entry Biologics Needs Assessment Results

The advent of biologics has improved patient outcomes in terms of patient survival as well as drug delivery. With many of Canada’s top selling biologic molecules facing patent expiration before 2020, a greater number of more affordable subsequent entry biologics (SEBs) will compete with ‘branded’ biologics. SEBs are ‘biologics that are similar to, and enter the market subsequent to, an approved innovator biologic’. These SEBs are of interest, yet present challenges. Certain issues and questions surrounding the differences between SEBs and biologics (eg. cost, manufacturing, approval processes, etc.), need to be considered as more SEBs are developed and become available. This needs assessment focuses on some of these issues. 

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CARE Perspectives ASH 2014

Members of the CARE Hematology Faculty attended the ASH 2014 conference held in San Francisco, California from December 6-9th 2014. The CARE at ASH education event was held with trainees and community hematologists from across Canada and covered various topics in hematology. This report provides an overview of the key abstracts and sessions from ASH discussed at this meeting, with Canadian perspectives provided by Faculty.

The report content that follows is drawn from ASH 2014 and is augmented with the CARE Hematology Faculty Canadian perspective and commentary. Full abstract content can be found on the ASH website at: ash.confex.com/ash/2014/webprogram/start.html

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CARE Perspectives CHC 2014

CARE (Community Academic Research Education) has successfully completed its fourth year of hosting the Canadian Hematology Conference (CHC), previously known as TLC, (Toronto Lymphoproliferative Conference). There was great attendance, made up of hematologist-oncologists from academic and community centres, supportive care repre- sentatives and pharmacists. Key news and developments were discussed in a number of different hematological malignancies. 

To show the comprehensive and multidisciplinary nature of CHC 2014, an abridged scientific programme and featured sessions are reviewed in the pages that follow. Chairs and presenters of each session are identified at the beginning of each section. 

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CARE Perspectives ASCO/EHA 2014

Members of the CARE Hematology Faculty met at the annual ASCO (American Society of Clinical Oncology) 2014 conference held in Chicago, IL from May 30th – June 3rd and at EHA (European Hematology Association) 2014 held in Milan, Italy from June 12-15th. The CORE at ASCO education event was held with trainees and community hematologists from across Canada and covered various topics in hematology. At this year’s ASCO, Dr. Kuruvilla presented to all of the residents in the CORE meeting, and then had a ‘deep dive’ session with hematology residents that further delved into issues in hematology. Additional content and abstracts have been included in this report from the European Hematology Association (EHA) conference (June 12th - 15th, 2014, Milano, Italy) as well as Princess Margaret Cancer Center’s Multiple Myeloma Day (June 13th, 2014, Toronto, ON). 

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CARE Perspectives IMW/CCOLD 2013

The CARE Hematology Faculty recently met at the 14th international Myeloma Workshop (IMW). CARE “Canadian Perspectives” shares news and developments in myeloma as covered at IMW, framed in a Canadian perspective, and is augmented with select content from the 2013 Canadian Conference on Lymphoproliferative Disorders (CCOLD).

Advanced treatment options and comprehensive prognosis, as well as risk factor guidelines, are showing promise to both physicians and patients of more effective, less toxic treatment regimens, leading to higher rates of survival in Multiple Myeloma.

Report content and visuals that follow are drawn from the presentations and abstracts at IMW 2013, as well as highlights from key presentations from CCOLD 2013. 

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CARE Perspectives ASCO/EHA 2013

The treatment of hematological malignancies is rapidly progressing, involving new therapies through a greater understanding of biologic mutations. The CARE Hematology Faculty met at the American Society of Clinical Oncology (ASCO) conference in Chicago, Illinois on May 31–June 4, 2013 to discuss news and developments in hematological oncology.

Report content and visuals that follow are a reprise of the presentations by Dr. John Kuruvilla and Dr. Rob Laister during the CORE (Canadian Oncology Resident Education) program and CARE Hematology Working Group meeting at ASCO 2013, framed from a Canadian perspective and augmented with key abstracts and plenary session content from the conference. Additional content and abstracts have been included from Princess Margaret Cancer Centre’s Multiple Myeloma Day (June 6, 2013; Toronto, Ontario), the European Hematology Association’s (EHA) 18th annual conference (June 13–16, 2013; Stockholm, Sweden) and the 12th annual International Conference on Malignant Lymphoma (ICML) (June 19–22, 2013; Lugano, Switzerland) showcasing evolving stories in this field. 

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CARE Perspectives CHC 2013

The third annual Canadian Hematology Conference – CHC 2013 (formerly the Toronto Lymphoproliferative Conference), ran over two days in late September. The conference format consisted of plenary sessions covering Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, plasma cell disorders, leukemia, and MDS. The format was designed to enhance education and promote discussion. Parallel sessions were also held. These focused on more in-depth discussion of emerging therapies, as well as specific pre-defined topics for Supportive CARE professionals (nurses & pharmacists).

To show the comprehensive and multidisciplinary nature of CHC 2013, we have provided an abridged scientific programme and featured sessions that were covered over the two days.

Report content and visuals that follow are drawn from these presentations, including abstract content and discussions. Commentary and perspectives have been provided by the CARE CHC Faculty. 

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CARE Perspectives ASH 2013

The CARE Hematology Faculty met at the American Society of Hematology (ASH) meeting in New Orleans, Louisiana, December 7–10, 2013.

The faculty presented key news and developments in hematology at the 2013 CARE @ ASH meeting to upwards of 80 Canadian trainees, fellows, community and academic-based specialists. The content and visuals that follow are drawn from these presentations, including abstract content and discussion from ASH 2013, framed from a Canadian perspective. 

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