CARE Guidance: Treatment Considerations for Advanced Prostate Cancer

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The 2017 CARE™ treatment considerations for advanced prostate cancer, considers updates and experiences of the contributing specialists identified below. Included is a suggested treatment algorithm, along with management considerations for mHSPC, CNSPC/CSPC and CRPC.

This guidance is based on experiences and perspectives of Canadian urologists, medical oncologists and radiation oncologists. The aim of this collaboration is to optimize patient outcomes by taking into account all other specialties who manage and treat patients with advanced prostate cancer.

 

CARE Faculty Who Have Contributed to This Report:

Dr. Alan So- BC Cancer Agency, Urology, Faculty Lead

Dr. Anil Kapoor- St. Joseph’s Healthcare, Urology

Dr. Brita Danielson- Alberta Health Services, Radiation Oncology, Faculty Lead

Dr. Denis Soulières- Centre hospitalier de l’Université de Montréal, Medical Oncology

Dr. Kim Chi- BCCA, Medical Oncology

Dr. Ricardo Rendon- QEII Health Sciences Centre, Urology

Dr. Sebastien Hotte- Juravinski Cancer Centre, Medical Oncology, Faculty Lead

Dr. Srikala Sridhar- Princess Margaret Cancer Centre, Medical Oncology

 

CARE Perspectives: ESMO 2017

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Members of the CARE Oncology Faculty recently met at the ESMO 2017 conference held in Madrid, Spain (September 8-12), and were joined by their Radiation and Urology Oncology contemporaries for a Working Group.

This year’s ESMO Congress partnered with the European Association for Cancer Research (EACR). Content focused on the importance of understanding the molecular biology underlying cancer development, in order to ultimately improve cancer therapy. 

CARE Faculty who have contributed to this report:

Dr. Rob El-Maraghi
Royal Victoria Regional Health Centre

Dr. Normand Blais
Centre hospitalier de l’Université de Montréal

Dr. Sebastien Hotte
McMaster University

Dr. Denis Soulières
Centre hospitalier de l’Université de Montréal

CARE Oncology & Hematology Guiding Principles on Biosimilars

This initiative is led by:
John Kuruvilla, MD, Rob El-Maraghi, MD, Peter Anglin, MD, Denis Soulières, MD & Stephen Chia, MD

The CARE Faculty has been looking at the impact of biosimilars since 2015, given the significance of this topic across both chronic and disease entities. Select CARE Oncology and Hematology Faculty members have consolidated the following guiding principles based on the collective discussion from past CARE Education initiatives that explored the anticipated impact that the introduction of biosimilars will have in Canada.

Biosimilars have been a topic of interest for various CARE™ Faculties for several years now. To gauge levels of understanding along with perceptions and opinions on the impact that biosimilars will have on the Canadian landscape, a number of CARE faculties conducted needs assessments with their peers. Between 2014-2016, needs assessments were directed at specialists in gastroenterology, rheumatology, oncology, and hematology.

The aim of developing these principles is to provide Canadian health care providers with an overarching view of the positions from the CARE Faculties, which in turn may help inform their treatment decisions.

 

CARE Perspectives: ASCO 2017

At ASCO 2017 (Chicago, Illinois – June 2-6), CARE Faculty members met to discuss the news and developments in the field of oncology.

Within this report, key abstracts and select plenary sessions have been summarized and augmented with perspectives from the CARE Faculty framed from a Canadian perspective. 

The content that follows is written in the language in which it was presented and is adapted from the abstracts presented at the ASCO 2017 conference. 

 

CARE FACULTY WHO HAVE CONTRIBUTED TO THIS REPORT:

Rob El-Maraghi, MD
Royal Victoria Regional Health Centre

Sebastien Hotte, MD
McMaster University

Denis Soulières, MD
CHUM

Kim Chi, MD
BC Cancer Agency

CARE Perspectives: GICS 2017

Highlights from GICS 2017

Members of the CARE Gastrointestinal Cancer Faculty recently attended the Gastrointestinal Cancers Symposium (GICS) 2017 conference held in San Francisco, CA from January 19-21.

The CARE Perspectives Conference Report from GICS 2017 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Gastrointestinal Cancer Faculty. 

CARE Gastrointestinal Cancer Faculty who have contributed to this report:

Sharlene Gill, MD, MPH
BC Cancer Agency 

Rob El-Maraghi, MD
Royal Victoria Regional Health Centre

 

CARE Perspectives: SABCS 2016

Highlights from SABCS 2016

Members of the CARE Breast Cancer Faculty recently attended the SABCS 2016 conference held in San Antonio, TX from December 6-10.

The CARE Perspectives Conference Report from SABCS 2016 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Breast Cancer Faculty. 

CARE Breast Cancer Faculty who have contributed to this report:

Stephen Chia, MD
BC Cancer Agency

Susan Dent, MD
The Ottawa Hospital Cancer Centre

 

CARE Perspectives: ESMO 2016

Highlights from ESMO 2016

Members of the CARE Oncology Faculty recently attended the ESMO 2016 conference held in Copenhagen, Denmark from October 7th-11th.

The CARE Perspectives Conference Report from ESMO 2016 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Oncology Faculty. 

CARE Oncology Faculty who have contributed to this report:

Christian Kollmannsberger, MD
University of British Columbia

Daniel Rayson, MD
Queen Elizabeth II Health Sciences Centre

Denis Soulières, MD
University of Montreal

 

 

 

CARE Perspectives: ASCO 2016

Members of the CARE Oncology Faculty spoke at the 11th annual CARE at ASCO 2016 meeting in order to educate Canadian trainees and residents as well as frame each of the developments from a Canadian perspective. Presentations featured cutting edge content with discussion on relevant cases and treatment strategies. CARE at ASCO was attended by over 50 Canadian oncology professionals. 

The CARE Perspectives Conference Report from ASCO 2016 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Oncology Faculty. 

I encourage you to attend the CARE at ASCO meeting in 2017 to learn about the highlights from ASCO, framed in a Canadian perspective. 

See you next year,

 

Denis Soulières, MD (Chair)
University of Montreal

 

CARE Perspectives: CLCCO 2016

The annual Canadian Lung Cancer Conference (CLCCO) 2016 was held in Vancouver, BC from February 11-12th. Presentations covered a number of exciting topics in lung cancer, with content relating to medical oncology, radiation oncology, surgical oncology, and supportive care. On Thursday February 11th, prior to the CLCCO conference, members of the CARE Faculty also held a Resident and Trainee Education Meeting. This meeting was chaired by Drs. Devin Shellenberg (Radiation Oncology, BCCA) and Randeep Sangha (Medical Oncology, Cross Cancer Institute), and included presentations from a number of Canadian and international KOLs (please visit the CARE website for more information and access to presentation content).  

This issue of CARE Perspectives will have a focus on the medical oncology content from both the conference as well as the Resident and Trainee meeting. A summary of the most relevant and compelling stories will be provided with additional commentary and perspectives from the CLCCO chair, and CARE Faculty member, Dr. Barb Melosky (BCCA). 

Onco-Times: Melanoma Needs Assessment Results

This needs assessment was distributed by mail and electronically in December 2015 to 400 Canadian oncologists working in academic teaching centres and/or community practices. 

In order to understand both current perception and knowledge as well as gaps in knowledge on the management of melanoma with Canadian medical oncologists, a needs assessment was conducted. The research is being led by Dr. Winson Cheung (BC Cancer Agency).

CARE Perspectives: ASCO GICS 2016

The annual ASCO GICS 2016 conference was held in San Francisco, California from January 21-23. There was a number of exciting abstracts and research presented at this conference. This issue of CARE Perspectives provides a summary of the most compelling stories and news presented at ASCO GICS, framed from a Canadian perspective. 

- Sharlene Gill, MD, MPH - BC Cancer Agency

 

CARE Perspectives: ASCO GUCS 2016

The annual ASCO GUCS 2016 conference was held in San Francisco, California from January 7-9. There was a number of exciting abstracts and research presented at this conference. A growing body of research has led to the development and approval of many agents in metastatic castrate resistant prostate cancer (mCRPC), and specialists face challenges regarding choice of therapy and sequencing of treatment options. For this reason, the focus of issue of CARE Perspectives is on prostate cancer. It provides a summary of the most compelling stories and news presented at ASCO GUCS, framed from a Canadian perspective. 

 

Oncology Year in Review 2015

There were a number of exciting developments in oncology this year. The CARE Oncology Year in Review 2015 is an interactive report that covers some of the most exciting stories in oncology throughout 2015. An overview of programs that different CARE faculties have developed in 2015 and upcoming conferences in 2016 have also been highlighted in this report.

CARE Perspectives SABCS 2015

The annual SABCS 2015 conference was held in San Antonio, Texas from December 8-12. There were a number of exciting abstracts and research presented at this conference. This issue of CARE Perspectives provides a summary of the most compelling stories and news presented at SABCS, framed from a Canadian perspective. 



CARE Perspectives: SMR 2015

Members of the CARE Oncology Faculty recently attended the 12th International Congress for the Society of Melanoma Research 2015 conference held in San Francisco, CA
(November 18-21).

The CARE Perspectives Conference Report from SMR 2015 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Oncology Faculty. 

CARE Perspectives ECC 2015

CLICK HERE TO VIEW THE FULL CARE PERSPECTIVES ON ECC REPORT

CLICK HERE TO VIEW THE FULL CARE PERSPECTIVES ON ECC REPORT

Members of the CARE Oncology Faculty recently met at the European Cancer Conference (ECC) 2015 conference held in Vienna, Austria from September 25-29. 

The CARE Perspectives Conference Report from ECC 2015 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspective from the CARE Oncology Faculty. 

Below is a link to the full report:

CLICK HERE FOR THE FULL REPORT.

CLICK HERE FOR THE FULL REPORT.

 

CARE Perspectives WCLC 2015

Click here to view the full CARE Perspectives on WCLC Report

Click here to view the full CARE Perspectives on WCLC Report

Members of the CARE Lung Cancer Faculty recently attended the World Conference on Lung Cancer (WCLC) 2015 conference held in Denver, Colorado on September 6-9.

The CARE Perspectives Conference Report from WCLC 2015 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Oncology Faculty.

This report includes information on the epidemiology, prevention and screening of lung cancer in Canada; the revised staging system in lung cancer; and both early and advanced stages of lung cancer.

Below is a link to the full report:

Click here for the full report.

Click here for the full report.

 

CARE Guidance: Treatment Considerations for mCRPC

Metastatic CRPC (mCRPC) has been a focus for the CARE Genitourinary Faculty since 2014, when they met at the American Society of Clinical Oncology (ASCO) annual meeting to discuss current challenges and considerations in the management of mCRPC. It was decided that multiple specialties (radiation oncology, urology, and medical oncology) needed to be involved in this discussion in order to provide their expertise and offer a variety of perspectives to the group. During the meeting at ASCO 2014, a CARE Treatment Guidance for mCRPC was developed. 

Since then, more data and agents have become available. Members of the CARE Faculty met at the Canadian Urological Association (CUA) – Canadian Urologic Oncology Group (CUOG) Multidisciplinary Meeting 2015 (June 27, 2015) to further discuss treatment options and considerations in this disease category, with the ultimate goal of updating and augmenting the previous CARE guidance document.

This document contains the updated CARE Treatment Guidance and provides additional details on the treatment options, including updated trial information on how the agent should be used, supporting recommendations from ASCO and Cancer Care Ontario (CCO), and supportive care issues. 

The development of this publication was led by CARE GU Faculty members Drs. Sebastien Hotte, Brita Danielson and Alan So, and includes insights/perspectives from other leading key opinion leaders from across Canada (please see guidance references for full details on specialists involved).

Below is a link to the full report:

CLICK HERE FOR THE FULL PUBLICATION

CLICK HERE FOR THE FULL PUBLICATION

 

CARE Perspectives CCOCO & ASCO 2015

Click here to read the full CARE Perspectives CCOCO & ASCO 2015 Conference Report. 

Click here to read the full CARE Perspectives CCOCO & ASCO 2015 Conference Report. 

Members of the CARE (Community, Academic, Research, Education) Oncology Faculty recently met at the CCOCO 2015 conference (Banff, AB – June 19-21) and attended ASCO 2015 (Chicago, IL - May 29 – June 2). Presentations were made on various topics in oncology at the CCOCO 2015 conference, as well as presentations and abstracts at ASCO. The annual CORE Resident and Trainee Education meeting at ASCO was held on May 29th where CARE Faculty members presented on a number of key topics in oncology.

The CARE Perspectives Conference Report from CCOCO and ASCO 2015 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspective from the CARE Oncology Faculty. 

Below is a link to the full report: 

Click here for the full report.

Click here for the full report.

 

CARE Perspectives ASCO Hematology 2015

Click here to view the full CARE Perspectives ASCO 2015 Hematology Conference Report. 

Click here to view the full CARE Perspectives ASCO 2015 Hematology Conference Report. 

Members of the CARE (Community. Academic. Research. Education) Oncology and Hematology Faculties recently met at the ASCO 2015 conference held in Chicago from May 29 – June 2. The CARE Resident and Trainee Education meeting was held on May 29th (8:00 am - 1:00 pm). At this meeting CARE Faculty members presented on a number of key topics in oncology, including hematology. The CARE Hematology Faculty then held a separate breakout session after the main meeting that took a deeper look at themes in hematology-oncology. The focus of their discussion was on indolent non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, multiple myeloma, and basic science for antibody drug conjugates. Additionally, due to the exciting news surrounding novel agents in the field of hematology, supportive care considerations for better patient symptom management were addressed at ASCO. This report covers some of the most important story lines in supportive care from ASCO.

The CARE Perspectives Conference Report from ASCO 2015 provides a summary of the most compelling stories and news presented at this event, and is augmented with additional perspectives from the CARE Hematology Faculty. 

Below is a link to the the full report:

Click here for the full report.

Click here for the full report.